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What is CML? | American Cancer Society Chronic myeloid leukemia (CML) is a type of cancer that starts in certain blood-forming cells of the bone marrow (the soft, spongy tissue in the middle of certain bones) It is also known as chronic myelogenous leukemia CML happens mostly in adults, but very rarely it happens in children, too
Chronic Myeloid Leukemia (CML): Symptoms, Treatment Prognosis Chronic myeloid leukemia (CML) is blood cancer that starts in the blood-forming myeloid cells or stem cells in your bone marrow The condition has other names: chronic myelogenous leukemia or chronic granulocytic leukemia
Chronic Myeloid Leukemia Treatment - NCI Chronic myeloid leukemia (also called CML or chronic myelogenous leukemia) is a slowly progressing blood and bone marrow disease that usually occurs during or after middle age and rarely occurs in children
Chronic myelogenous leukemia - Wikipedia Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells It is a form of leukemia characterized by the increased and unregulated growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood
Chronic Myeloid Leukemia (CML) - MD Anderson Cancer Center Chronic myeloid leukemia (CML) is a slow-growing form of the disease that primarily impacts people over age 55 Leukemia is an umbrella term for cancers of the blood and the blood-forming tissues of the body
Chronic Myeloid Leukemia (CML) - The Merck Manuals Chronic myeloid leukemia (CML) occurs when a pluripotent stem cell undergoes malignant transformation and clonal myeloproliferation, leading to a striking overproduction of mature and immature granulocytes
Chronic Myelogenous Leukemia - Johns Hopkins Medicine It occurs mainly in adults Scientists have long known that in CML patients, chromosomes 9 and 12 fuse together to form the “Philadelphia” chromosome The Philadelphia chromosome overproduces an enzyme called tyrosine kinase causing the bone marrow to make too many white blood cells
Chronic Myeloid Leukemia: A Review - JAMA Network Importance Chronic myeloid leukemia (CML) has an annual incidence of 2 cases per 100 000 people and is newly diagnosed in approximately 9300 individuals per year in the US Approximately 150 000 people in the US and 5 million worldwide have CML