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Repatha: Uses, Dosage, Side Effects Warnings - Drugs. com Repatha is used to lower high cholesterol alongside dietary changes and to reduce the risk of major cardiovascular events in those with cardiovascular disease, such as death from cardiovascular disease, heart attack, stroke, angina requiring hospitalization, or certain types of heart surgery It is given as an injection under the skin (subcutaneously), every 2 weeks or 1 time each month
How fast does Repatha work? - Drugs. com How fast does Repatha reduce the risk of cardiovascular events? In the first year on Repatha in the Fourier Clinical trial, there was a 12% risk reduction in the group of cardiovascular events including cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization
Repatha Dosage Guide - Drugs. com Detailed dosage guidelines and administration information for Repatha (evolocumab) Includes dose adjustments, warnings and precautions
How does Repatha work? - Drugs. com Repatha is used to prevent heart attacks, strokes and the need for coronary revascularization in those with existing cardiovascular disease It is also used to reduce low-density lipoprotein (LDL) or ‘bad’ cholesterol in certain people with hyperlipidemia or hypercholesterolemia
Repatha (evolocumab) FDA Approval History - Drugs. com Repatha FDA Approval History Last updated by Judith Stewart, BPharm on Sep 27, 2021 FDA Approved: Yes (First approved August 27, 2015) Brand name: Repatha Generic name: evolocumab Dosage form: Injection Company: Amgen Inc Treatment for: High Cholesterol; Prevention of Heart Attack and Stroke Repatha (evolocumab) is a monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin kexin
Is Repatha effective without a statin? - Drugs. com Yes, Repatha is effective at reducing low-density lipoprotein cholesterol (LDL-C) levels when taken on its own, without an additional statin In the 52 weeks clinical trial DESCARTES they compared placebo treatment, with Repatha on its own, Repatha with 10mg d of atorvastatin, and Repatha with 80mg d of atorvastatin
Why was Repatha Pushtronex discontinued and replaced? Repatha Pushtronex was discontinued in order to uphold Amgen’s standards for patient experience and care It was not discontinued because of safety or efficacy concerns At this time, patients without homozygous familial hypercholesterolemia (HoFH) or a latex allergy should use the Repatha SureClick autoinjector