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Myotonic dystrophy type 2 | About the Disease | GARD Proximal myotonic myopathy, one of the two types of myotonic dystrophy, is an inherited muscular dystrophy that affects the muscles and other body systems (e g , heart, eyes, and pancreas) It is characterized by prolonged muscle tensing (myotonia) as well as muscle weakness, pain, and stiffness Signs and symptoms usually develop during a person's twenties or thirties Muscles in the neck
Myotonic Dystrophy type 2 (DM2) Myotonic Dystrophy type 2 (DM2) DM2 was previously named “proximal Myotonic Myopathy” or “PROMM” and shares many of the clinical and genetic features of DM1 It is probably more common in central Europe and the USA than the rest of the world
Myotonic Dystrophy: What It Is, Symptoms, Types Treatment Myotonic dystrophy type 2 (DM2), also known as proximal myotonic myopathy Their symptoms overlap, but DM2 tends to be milder than DM1 What is the difference between muscular dystrophy and myotonic dystrophy? Muscular dystrophy refers to a group of more than 30 inherited (genetic) conditions that cause muscle weakness
Signs and Symptoms of Adult-Onset DM1 and DM2 - Myotonic Dystrophy (DM . . . The classic form of DM1 becomes symptomatic between the second and fourth decades of life In these patients, average lifespan is reduced Patients diagnosed with DM1 have multiple sets of DNA bases repeats in their genome (known as the CTG repeats) The CTG repeat size in adult onset is generally in the range of 50 to 1,000 1 The mild form of DM1 is characterized by mild weakness, myotonia
Myotonic dystrophy - Wikipedia Myotonic dystrophy (DM) is a type of muscular dystrophy, a group of genetic disorders that cause progressive muscle loss and weakness [1] In DM, muscles are often unable to relax after contraction [1] Other manifestations may include cataracts, intellectual disability and heart conduction problems [1][2] In men, there may be early balding and infertility [1] While myotonic dystrophy can
DM2 | Myotonic Dystrophy Foundation DM2 Myotonic dystrophy type 2, also known as proximal myotonic myopathy (PROMM), is a milder form of myotonic dystrophy in which transient muscle pain is the most common complaint Only adult-onset forms of DM2 have been recognized To date, there have been few large scale or definitive studies to determine the prevalence of DM2
Entry - #602668 - MYOTONIC DYSTROPHY 2; DM2 - OMIM MYOTONIC DYSTROPHY 2; DM2 Alternative titles; symbols DYSTROPHIA MYOTONICA 2 PROXIMAL MYOTONIC MYOPATHY; PROMM MYOTONIC MYOPATHY, PROXIMAL RICKER SYNDROME Phenotype-Gene Relationships Location Phenotype Phenotype MIM number Inheritance Phenotype mapping key Gene Locus Gene Locus MIM number 3q21 3 Myotonic dystrophy 2 602668 AD 3 CNBP 116955
Myotonic dystrophy type 2 (DM2) - Muscular Dystrophy UK Myotonic dystrophy type 2 (DM2) is a genetic muscle condition causing progressive weakness, stiffness, and pain, with possible heart, lung, and digestive involvement Learn about symptoms, diagnosis, and management
Myotonic dystrophy: Treatment and prognosis - UpToDate Discover treatment options and prognosis for myotonic dystrophy, a condition affecting muscles and other systems, with comprehensive insights on management strategies