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Ehlers-Danlos syndrome - Symptoms and causes - Mayo Clinic Overview Ehlers-Danlos syndrome is a group of inherited disorders that affect your connective tissues — primarily your skin, joints and blood vessel walls Connective tissue is a complex mixture of proteins and other substances that provide strength and elasticity to the underlying structures in your body
Ehlers-Danlos syndrome - Diagnosis and treatment - Mayo Clinic Diagnosis Extremely loose joints, fragile or stretchy skin, and a family history of Ehlers-Danlos syndrome are often enough to make a diagnosis Genetic tests on a sample of your blood can confirm the diagnosis in rarer forms of Ehlers-Danlos syndrome and help rule out other problems For hypermobile Ehlers-Danlos syndrome, the most common form, there is no genetic testing available
Sacroiliitis - Symptoms and causes - Mayo Clinic Sacroiliitis (say-kroe-il-e-I-tis) is a painful condition that affects one or both sacroiliac joints These joints sit where the lower spine and pelvis meet Sacroiliitis can cause pain and stiffness in the buttocks or lower back, and the pain might go down one or both legs Standing or sitting for a long time or climbing stairs can make the pain worse