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FDA approves sotorasib with panitumumab for colorectal cancer On January 15, 2025, the Food and Drug Administration approved sotorasib (Lumakras, Amgen Inc ) with panitumumab (Vectibix, Amgen Inc ) for adult patients with KRAS G12C-mutated metastatic
FDA APPROVES LUMAKRAS® (SOTORASIB) IN COMBINATION WITH . . . In June 2017, the FDA approved a refined indication for Vectibix for use in patients with wild-type RAS (defined as wild-type in both KRAS and NRAS as determined by an FDA-approved test for this use) mCRC, specifically as first-line therapy in combination with FOLFOX and as monotherapy following disease progression after prior treatment with
U. S. Food and Drug Administration Approves Opdivo® (nivolumab . . . U S Food and Drug Administration Approves Opdivo® (nivolumab) plus Yervoy® (ipilimumab) as a Treatment for Patients with Previously Untreated Microsatellite Instability-High or Mismatch Repair Deficient Unresectable or Metastatic Colorectal Cancer
FDA Oks Sotorasib Panitumumab in KRAS G12C-Mutant Colorectal . . . The approval of this combination is supported by data from the phase 3 CodeBreaK 300 study The FDA has approved the combination of sotorasib (Lumakras) and panitumumab (Vectibix) for the treatment of patients with previously treated KRAS G12C-mutated metastatic colorectal cancer (CRC) The approval
U. S. FDA Approves Pfizer’s BRAFTOVI® Combination Regimen as . . . This release contains forward-looking information about the BRAFTOVI® (encorafenib) plus cetuximab and mFOLFOX6 combination and a new indication in the U S for the treatment of patients with metastatic colorectal cancer (CRC) with a BRAF V600E mutation, as detected by an FDA-approved test, including their potential benefits and discussions
FDA Approves First Colorectal Cancer Treatment that Targets . . . The targeted therapy adagrasib received accelerated approved for colorectal cancer caused by a mutation called KRAS-G12C, when used in combination with the drug cetuximab MSK investigators have led much of the research that resulted in this combined drug approval