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Home - Escient pharmaceuticals Escient strives to discover and develop novel, life-changing medicines for patients We are committed to advancing innovative solutions for some of the most challenging, underserved disorders worldwide, where current treatments are either insufficient or nonexistent
Press Releases - Escient pharmaceuticals Escient Pharmaceuticals Launches with $40 Million Series A Financing to Advance First-in-Class G Protein-Coupled Receptor (GPCR)-Targeted Drugs to Address Serious, Unserved Medical Needs
Incyte Completes Acquisition of Escient Pharmaceuticals - Escient . . . The company’s pipeline includes two first-in-class small molecule antagonists targeting MRGPRX2 for the treatment of various mast cell mediated disorders and MRGPRX4 for cholestatic pruritus Based in San Diego, California, Escient is led by an experienced management and scientific team and funded by top-tier life science investors
Escient Pharmaceuticals Announces IND Clearance by FDA to Start Phase 1 . . . SAN DIEGO, Calif , January 30, 2023 — Escient Pharmaceuticals, a clinical-stage company advancing novel small molecule therapeutics for the potential treatment of a broad range of neurosensory-inflammatory disorders, today announced that the U S Food and Drug Administration (FDA) has cleared the company’s Investigational New Drug (IND
MRGPRX2 - Escient pharmaceuticals Escient is developing EP262, an oral, once-daily, small molecule antagonist of Mas-related G protein-coupled receptor X2 (MRGPRX2) for the potential treatment of a variety of mast cell-mediated diseases, with an initial focus on chronic urticarias and atopic dermatitis
Scientific Publications - Escient pharmaceuticals MRGPRX2 Small Molecule Antagonists Potently Inhibit Agonist-Induced Skin Mast Cell Degranulation EAACI 2023 Annual Meeting Joshua Wollam, Michelle Solomon, Christiane Villescaz, Samantha Anderson, David Freeman, Alexis Vasquez, Corinne Pisacane, Alan Vest, Jim Napora, Brittney Charlot, Christine Cavarlez, Lisa Dvorak, Andrew Kim, Marion Lanier, Brandon Selfridge, Liming Huang, Marcos Sainz
Leadership - Escient pharmaceuticals Joshua Grass, Chief Executive Officer, joined Escient in December 2021 Most recently, Josh was Chief Executive Officer from 2017 to 2019 of Modis Therapeutics, a company developing a treatment for a rare mitochondrial disease
Overview - Escient pharmaceuticals We are a privately held, clinical stage biotechnology company advancing novel, differentiated therapeutics for the potential treatment of a broad range of neurosensory-inflammatory disorders Neural activation of the immune system plays an important role in numerous clinical conditions, and recent scientific advances have provided new avenues for therapeutic intervention
For Patients - Escient pharmaceuticals At Escient, we are driven by and passionate about making a positive difference in the lives of patients Through cutting edge science, we strive to discover and develop novel, life-changing medicines