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Formins - Wikipedia Formins (formin homology proteins) are a group of proteins that are involved in the polymerization of actin and associate with the fast-growing end (barbed end) of actin filaments [2]
Formins at a glance - PMC Formins are conserved actin polymerization machines that have instrumental roles in controlling rearrangements of the actin cytoskeleton and have recently been shown to directly regulate microtubule dynamics
Formin Protein: Function, Regulation, and Importance Formin proteins are a family of proteins involved in constructing and regulating the cell’s internal scaffolding, known as the actin cytoskeleton This cytoskeleton provides a cell with its shape and enables various movements and internal organization
Mechanisms of actin filament severing and elongation by formins Humans express 15 formins that play crucial roles in actin-based processes, including cytokinesis, cell motility and mechanotransduction 1, 2 However, the lack of structures bound to the actin
What is the role of formin in actin polymerization . . . The FH2 domains of the formin dimer (shown in green) bind to actin monomers to initiate filament assembly Recent studies indicate this is assisted, or even mediated, by additional factors such as APC
Formins - an overview | ScienceDirect Topics Formins are a group of ubiquitous multi-domain proteins that catalyse the nucleation and elongation of linear actin filaments by insertional assembly of monomers to the fast growing barbed ends