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Hydroxychloroquine-Induced Retinal Toxicity - Patients - The American . . . Hydroxychloroquine (HCQ), sold under the brand name Plaquenil, is a medication used to treat autoimmune diseases like rheumatoid arthritis and lupus While it is very effective, long-term use can cause serious eye problems, including retinal damage and vision loss
Hydroxychloroquine-induced Retinal Toxicity - PMC Long-term use of hydroxychloroquine can cause retinopathy, which may result in severe and progressive visual loss In the past decade, hydroxychloroquine use has markedly increased and modern retinal imaging techniques have enabled the detection of early, pre-symptomatic disease
Plaquenil Toxicity and Protecting Your Vision – Philadelphia Plaquenil can cause retinal damage in roughly 1 in 1,000 users over a five-year period About 7 5 percent of long-term users experience eye changes, and the number rises to nearly 20 percent after 20 years Because vision loss from toxicity is irreversible, early detection is essential
Understanding Plaquenil Toxicity and Its Impact on Eye Health Plaquenil toxicity occurs when the drug accumulates in the retinal cells, potentially leading to vision changes While the risk is low with proper dosing, it increases with the duration of use, making awareness and regular screening essential for long-term safety
Effect of Long-Term Plaquenil Use on Dry Age-Related Macular . . . Pathologic manifestations of dry age-related macular degeneration (ARMD) mimic those observed with Plaquenil use like thinning and disruption of the outer retinal layer This observational study aims to investigate whether long term Plaquenil use is associated with progression of dry ARMD
Plaquenil Toxicity | 5 Retina Centers Serving Philadelphia Plaquenil (hydroxychloroquine) is a widely prescribed medication for autoimmune diseases such as lupus and rheumatoid arthritis However, with long-term use, it can lead to retinal toxicity—an irreversible condition that may continue to progress even after the medication is discontinued
Hydroxychloroquine Toxicity - EyeWiki Patients are at low risk during the first 5 years of treatment At recommended doses, the risk of toxicity up to 5 years is under 1% and up to 10 years is under 2%, but it rises to nearly 20% after 20 years