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CPTAC Investigators Assess Coring and Laser Microdissection Techniques . . . In an effort to overcome this obstacle, a group of researchers from the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC), enriched neoplastic cells from bulk tumor using coring and laser microdissection (LMD) sampling techniques; and compared the proteogenomic signatures among samples
Office of Cancer Clinical Proteomics Research The Clinical Proteomic Tumor Analysis Consortium (CPTAC) has performed proteogenomic characterization for over 1,000 primary tumors spanning 10 cancer types: breast invasive carcinoma (BRCA), clear cell renal cell carcinoma (CCRCC), colon adenocarcinoma (COAD), glioblastoma (GBM), head and neck
proteomics. cancer. gov CPTAC Breast Cancer Plasma CptacParticipantId DateOfBiopsyProcedure NADateOfBiopsyProcedure
News and Announcements | Office of Cancer Clinical Proteomics Research This platform, developed by CPTAC researchers at the Icahn School of Medicine at Mount Sinai and published in Cell Reports Methods, integrates transcriptomics, proteomics, and phosphoproteomics data to identify potential therapeutic targets and is capable of generating detailed reports automatically
Assay Portal | Office of Cancer Clinical Proteomics Research The CPTAC Assay Portal serves as a centralized public repository of "fit-for-purpose," multiplexed quantitative mass spectrometry-based proteomic targeted assays Targeted proteomic assays eliminate issues that are commonly observed using conventional protein detection systems
Progress in Proteomics: Fernanda Martins Rodrigues, Ph. D. With CPTAC, however, we introduced the concept of personalized proteogenomics, where we looked at the impact of common and rare germline variants into the proteome and post-translational modification sites in a way that we hadn’t been able to do before
PowerPoint Presentation What’s next for CPTAC Recommendations: build on the achievements of CPTAC to accelerate molecularly oriented cancer research toward basic discovery and clinical impact (achieved through goals 1 and 2)