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OCA2 Gene - GeneCards | P Protein | P Antibody This gene encodes the human homolog of the mouse p (pink-eyed dilution) gene The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis
SCP2 Gene - GeneCards | SCP2 Protein | SCP2 Antibody This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters
BRCA2 Gene - GeneCards | BRCA2 Protein | BRCA2 Antibody Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair
CHEK2 Gene - GeneCards | CHK2 Protein | CHK2 Antibody The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage