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Roles of HMGA proteins in cancer - Nature Reviews Cancer Here, we focus on the role of the HMGA proteins in human neoplastic diseases, the mechanisms by which they contribute to carcinogenesis, and therapeutic strategies based on targeting HMGA
HMGA and Cancer - ScienceDirect Here, we review the involvement of HMGA proteins in cancer, analyzing the mechanisms underlying their crucial role in tumorigenesis, and, finally, discuss the potentiality of a cancer treatment based on HMGA targeting
HMGA2 as a Critical Regulator in Cancer Development - PMC Importantly, HMGA2 is re-expressed in nearly all human malignancies, where it promotes tumorigenesis by multiple mechanisms HMGA2 increases cancer cell proliferation by promoting cell cycle entry and inhibition of apoptosis
HMGA2 as a Critical Regulator in Cancer Development In this review, we discuss these oncogenic roles of HMGA2 in different types of cancers and propose that HMGA2 may be used for cancer diagnostic, prognostic, and therapeutic purposes
Complicated crosstalk between HMGA and non-coding RNAs modulates . . . High mobility group A1 (HMGA1) is a class of non-histone chromosomal protein and is highly expressed in the embryonic period and many tumors It is involved in multiple hallmarks of tumors and affects the occurrence and progression of tumors