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BRAF in Melanoma BRAF is a gene that tells your cells how to grow A BRAF mutation is a change in a BRAF gene That change in the gene can lead to an alteration in a protein that regulates cell growth that could allow the melanoma to grow more aggressively Approximately half of melanomas carry this mutation and are referred to as mutated, or BRAF positive Melanomas that do not carry the mutation are referred
BRAF in Melanoma - AIM at Melanoma Foundation Stage III and IV patients who are BRAF positive have increased treatment options, so it is critical that you know whether you are BRAF positive in order to know what all of your treatment options are Some Stage II melanoma patients, in the context of a clinical trial, may undergo BRAF testing
BRAF Mutation and Cancer - Johns Hopkins Medicine BRAF gene mutations can cause normal cells to become cancerous Learn about the mutation, the types of cancer it can cause and the treatments available
BRAF-Mutated Melanoma: What It Is and How It’s Treated The results classify the melanoma as either BRAF-positive (if a mutation is found) or BRAF-negative (wild-type), a distinction that is fundamental for treatment planning for melanoma that has spread or cannot be surgically removed
BRAF Mutation Melanoma: Testing, Treatments, Prognosis Therapies aimed at the BRAF mutation have significantly improved the outlook for patients with advanced melanoma While a BRAF-positive diagnosis can indicate an aggressive cancer, it also means that highly effective treatments are available These options have transformed the prognosis for a disease that once had very limited options
BRAF Q A - The Melanoma Hub BRAF in Melanoma: Answering Questions, Addressing Misconceptions In the resources provided below, the faculty provides answers to questions and addresses misconceptions raised by patients regarding BRAF in melanoma The patient-directed resources address what BRAF is, the role of BRAF in melanoma, what BRAF mutational status means, testing for BRAF, and the implications of the test results for
BRAF Mutations in Melanoma: Biological Aspects, Therapeutic . . . Cutaneous melanoma represents the most aggressive form of skin cancer and its occurrence, development, and progression are based on the accumulation of several genetic alterations BRAF mutations are frequently found in melanoma and targeted