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Peritoneal Fluid Analysis • LITFL • CCC Investigations Exudate Serum:Ascites Ratios Evidence for these ascites:serum ratios is controversial Ascitic fluid protein Serum Protein >0 5; Ascitic Fluid LDH Serum LDH >0 6; Ascitic Fluid LDH >400; Presence of any 2 of these three findings is usually associated with TB, Malignancy or Pancreatitis; Absence of all three usually indicates hepatic cause
Evaluation of adults with ascites - UpToDate Successful treatment of ascites depends upon an accurate diagnosis of its cause (table 1 and table 2 and table 3) This topic will review the evaluation of adults with ascites Performance of paracentesis, the initial therapy of ascites in patients with cirrhosis, and the treatment of refractory ascites are discussed in detail separately
Ascitic Fluid Analysis in the Differential Diagnosis of Ascites: Focus . . . Ascitic fluid total protein and the serum-ascites albumin gradient (SAAG) For many years, the ascitic total protein concentration has been used to determine whether ascitic fluid was a transudate or exudate 2 However, this paradigm was flawed and resulted in frequent misclassifications
Unexplained ascites - PMC Differential Diagnosis of Ascites: Fluid Albumin, Protein, and Differential Cell Count Are the Key for Diagnosis Table 1 summarizes the key elements that are important in the differential diagnosis of ascites The most important parameter to determine the cause of ascites is the serum‐ascites albumin gradient (SAAG)
Ascites with elevated protein content as the presenting sign of . . . A serum-ascites albumin gradient ≥1 1 g dL and an ascites fluid total protein >2 5 g dL is typical of constrictive pericardial disease and other postsinusoidal causes of ascites Sinusoidal diseases, such as liver cirrhosis, exhibit a serum-ascites albumin gradient >1 1 g dL but an ascites fluid total protein <2 5 g dL
Interpreting sample results in ascites - Oxford Medical Education Traditionally the serum: ascites LDH and protein ratios help differentiate exudates from transudates However, the literature shows that these calculations are actually not helpful The Serum Ascites Albumin Gradient (SAAG), a concept involving oncotic-hydrostatic balance, has become the preferred measurement to characterize ascites
Ascites (Nursing) - StatPearls - NCBI Bookshelf Ascitic fluid protein and albumin are measured simultaneously with the serum albumin level to calculate the serum-ascites albumin gradient (SAAG) The presence of a gradient greater or equal to 1 1 g dL (greater or equal to 11 g L) predicts that the patient has portal hypertension with 97% accuracy
Ascitic Fluid Analysis | Ascites Interpretation | Geeky Medics Serum ascitic albumin gradient (SAAG) The serum ascitic albumin gradient (SAAG) indirectly measures portal pressure and can be used to determine if ascites is due to portal hypertension SAAG calculation SAAG = (serum albumin) – (ascitic fluid albumin) Interpretation A high SAAG (>11 g L) suggests the ascitic fluid is a transudate
Evaluation of New-Onset Ascites - PMC - PubMed Central (PMC) The SAAG and ascites protein levels are most useful for distinguishing among the 3 main causes of ascites The patient has an elevated SAAG (≥1 1 g dL), which is found in both heart failure and cirrhosis-related ascites Though diagnostic paracentesis is the standard first step for evaluating new-onset ascites, serum brain natriuretic
New Biochemical Parameters in the Differential Diagnosis of Ascitic . . . Serum protein concentration and portal pressure determine the ascitic fluid protein concentration in patients with chronic liver disease J Lab Clin Med 1983;102(2):260–273 [Google Scholar] 9 Pare P, Talbot J, Hoefs JC Serum-ascites albumin concentration gradient: a physiologic approach to the differential diagnosis of ascites