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Body weight and fat mass across the menopausal transition . . . A prominent role has been found for the estrogen receptor (ER) alpha isoform in fat accrual Human studies suggest a role for androgens in central fat accumulation and type 2 diabetes FSH is a key factor in the process of fat accumulation, but only in rodents
Obesity and menopause - ScienceDirect Estrogen replacement has been shown in both animal and human studies to reverse the estrogen depletion associated with weight gain and body fat redistribution [16, 24, 31] Several studies have shown a beneficial effect of hormone therapy in the reduction of central adiposity and preservation of lean body mass, including the WHI and PEPI
Estrogen Deficiency and the Origin of Obesity during Menopause Sex hormones strongly influence body fat distribution and adipocyte differentiation Estrogens and testosterone differentially affect adipocyte physiology, but the importance of estrogens in the development of metabolic diseases during menopause is