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Company Name: Corporate Name:	NETWORKS-NETWORKS
Company Title:	Reiki Professors
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Company Address:	47 Chase St,DANVERS,MA,USA
ZIP Code: Postal Code:	1923
Telephone Number:	9787775732 (+1-978-777-5732)
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Website:	reikiprofessors. net
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USA SIC Code(Standard Industrial Classification Code):	737904
USA SIC Description:	Computers
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The effects of linkage disequilibrium in large scale SNP datasets for . . .
When trying to assess sensitivity from such analytical methods, a confounding factor up to this point has been the presence of linkage disequilibrium (LD) In this study, we examined the effect of LD on the sensitivity of the Multifactor Dimensionality Reduction (MDR) software package
Confounding by linkage disequilibrium - Nature
As a proof-of-concept study for the phenomenon of confounding by LD, we analyzed the LD pattern among Chr 1q43 single nucleotide polymorphisms (SNPs) at risk for UL and or obesity in the
Determinant-based grouping of SNPs and its application for detecting . . .
Here, we introduce a novel approach for SNP grouping, leveraging the determinant of linkage disequilibrium (LD) matrices as a comprehensive metric of multicollinearity
Efficiency of different strategies to mitigate ascertainment bias when . . .
Methods of SNP discovery have been a matter of debate for their potential of introducing ascertainment bias, and genetic diversity results obtained from the SNP genotype data can be misleading
Frontiers | Pure and Confounded Effects of Causal SNPs on Longevity . . .
This study suggests that differences in LD levels between two causal SNP loci within two study populations may contribute to the failure to replicate previous GWAS findings
Challenges of Adjusting Single-Nucleotide . . . - Karger Publishers
Methods of post-GWAS analysis, including gene-based, gene-set and polygenic risk scores, combine the SNP effect sizes in an attempt to boost the power of the analyses To avoid giving undue weight to SNPs in linkage disequilibrium (LD), the LD needs to be taken into account in these analyses
LD in Bioinformatics: A Deep Dive - numberanalytics. com
By examining the LD patterns, researchers can identify a smaller set of SNPs that are in high LD with the associated SNP and are therefore more likely to be causal
Drivers of linkage disequilibrium across a species’ geographic range
Abstract While linkage disequilibrium (LD) is an important parameter in genetics and evolutionary biology, the drivers of LD remain elusive Using whole-genome sequences from across a species’ range, we assessed the impact of demographic history and mating system on LD
Confounding of linkage disequilibrium patterns in large scale DNA based . . .
The success of GWAS using SNPs as genetic markers in part relies on Linkage Disequilibrium (LD) as a population concept LD is a property of SNPs in a genomic sequence that refers to allelic association and linkage
Systematic Heritability and Heritability Enrichment Analysis for . . .
Genome-wide association studies (GWAS) have identified >300 genetic loci associated with type 2 diabetes Together these top GWAS signals explain >19% of the phenotypic variance in risk for the type 2 diabetes risk (1)