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Hypoparathyroidism - Symptoms causes - Mayo Clinic Hypoparathyroidism is a rare condition in which the body doesn't make enough of a key hormone called parathyroid hormone (PTH) PTH helps control and maintain the right balance of two minerals in the body: calcium and phosphorus With hypoparathyroidism, too little PTH leads to unusually low levels of calcium in the blood It also leads to high levels of phosphorous in the blood
Hypoparathyroidism and Pseudohypoparathyroidism In primary hypoparathyroidism with hypocalcemia and hyperphosphatemia, deficient parathyroid hormone (PTH) secretion most commonly occurs from surgical excision of, or damage to, the parathyroid glands The term idiopathic hypoparathyroidism describes isolated cases when a cause is not obvious, and there is no family history However, hypoparathyroidism is also a feature common to a variety of
Hypoparathyroidism: Symptoms Treatment - Cleveland Clinic Hypoparathyroidism Hypoparathyroidism is a rare but treatable condition that causes low levels of calcium in your blood Damage to your parathyroid glands during surgery and certain genetic and autoimmune diseases can cause it Treatment usually involves calcium and vitamin D supplements
Types Causes of HypoPARAthyroidism Genetic HypoPARAthyroidism Symptoms of genetic hypoPARA present in the first few years of life, absent surgical causes There is often a family history of the condition Genetic hypoPARA may be part of a syndrome involving other organs or tissues, such as: DiGeorge Syndrome Kenny-Caffey Syndrome Autoimmune Polyglandular Syndrome (APS-1) Pearson
Understanding Inherited Hypoparathyroidism: Causes, Symptoms . . . Inherited hypoparathyroidism is a rare genetic disorder that affects the parathyroid gland's ability to produce parathyroid hormone (PTH) This hormone is responsible for regulating calcium levels in the body In this article, we will explore the causes, symptoms, and treatment options for inherited hypoparathyroidism
Hypoparathyroidism: An Overview of Causes, Symptoms, and . . . Hypoparathyroidism is a complex condition with various causes and significant implications for calcium and phosphate homeostasis Early diagnosis and appropriate management are crucial for alleviating symptoms and preventing complications
From genes to glands: The genetic framework of parathyroid . . . Hypoparathyroidism-related genetic mutations In contrast, hypoparathyroidism results from inadequate PTH production, leading to hypocalcemia and associated neuromuscular symptoms Genetic causes of hypoparathyroidism are less common but can be highly significant in certain populations
Hypoparathyroidism: Genetics and Diagnosis - Oxford Academic Several genetic disorders can present with hypoparathyroidism, either as an isolated disease or as part of a syndrome A positive family history and, in the case of complex diseases, characteristic comorbidities raise the clinical suspicion of a genetic disorder