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Holliday junction - Wikipedia Robin Holliday proposed the junction structure that now bears his name as part of his model of homologous recombination in 1964, based on his research on the organisms Ustilago maydis and Saccharomyces cerevisiae
Holliday Model of DNA Recombination | PPTX - SlideShare Introduces the Holliday Model, discovered in 1964, which explains genetic recombination processes Defines duplex and heteroduplex DNA structures important for genetic recombination Outlines the sequential steps in the Holliday Model including alignment, nick formation, and resolution
8. 6: Holliday Model for General Recombination - Single Strand Invasion . . . This shows the steps in the Holliday model in a movie, illustrating the actions much more vividly than static diagrams The recombinant joint proposed by Holliday has been visualized in electron micrographs of recombining DNA duplexes (Figure 8 7A)
DNA Holliday Junction: History, Regulation and Bioactivity DNA Holliday junction (HJ) is a four-way stranded DNA intermediate that formed in replication fork regression, homology-dependent repair and mitosis, performing a significant role in genomic stability
Recombination Models (Holliday Model) | PDF | Dna | Base Pair The model outlines the steps of homologous pairing, strand invasion to form heteroduplex DNA, branch migration, and resolution of the Holliday junction which can result in crossover or non-crossover products
Holliday Junction - an overview | ScienceDirect Topics Holliday junction is defined as a four-way junction in DNA formed by the mutual exchange of strand connectivity, serving as a central intermediate in genetic recombination during the repair of double-strand DNA breaks
Prokaryotic DNA Crossroads: Holliday Junction Formation and Resolution In essence, this model prominently features the formation of a region of heteroduplex DNA after the exchange of DNA strands, ultimately resulting in the resolution of the HJ into two recombinant DNA molecules, categorized as either “spliced crossovers” or “patched non-crossovers”