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Pathology Outlines - PAS (Periodic acid-Schiff) PAS (Periodic acid-Schiff) is a special stain, not an immunostain, that stains basement membrane (normal and in tumors), glycogen, some mucins and mucopolysaccharides
Pathology Outlines - Hidradenitis suppurativa Hidradenitis suppurativa is a chronic inflammatory disorder of pilosebaceous apocrine unit characterized by nodules, abscesses, fistulae and sinus tracts with scarring that most commonly affects the axillae and groin among other areas of young adults
Pathology Outlines - Radial scar complex sclerosing lesion Breast nonmalignant - Radial scar complex sclerosing lesionBenign breast lesion comprised of a central fibroelastotic stromal core with radiating ducts and lobules with varying degrees of proliferative and cystic changes arranged in a stellate configuration May simulate invasive carcinoma mammographically, clinically, grossly and microscopically Atypia or malignancy may arise within or in
Pathology Outlines - Hamartoma Hamartoma is a well circumscribed, often encapsulated mass composed of normal but disorganized components of breast tissue
Pathology Outlines - Gynecomastia Breast nonmalignant - Gynecomastia - benign enlargement of the male breast, typically presenting as a palpable subareolar mass
Pathology Outlines - Paget disease Mammary Paget disease (MPD) is a proliferation of malignant glandular epithelial cells (in situ carcinoma) in the nipple areolar epidermis
Pathology Outlines - Alcian blue Stains acid-simple, nonsulfated and acid-simple mesenchymal mucins at pH 2 5, acid-complex sulfated mucins at pH 1 0 and acid-complex connective tissue mucins at pH 0 5; does NOT stain neutral mucins PAS-Alcian blue may be best pan mucin combination; PAS also stains glycogen, but predigestion with diastase will remove the glycogen Alcian blue-high iron diamine detects sulfomucins (brown) and