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Biologics for eosinophilic oesophagitis: a systematic review . . . The therapeutic efficacy of biologics for EoE and other non-EoE EGIDs is still under debate Therefore, we aim to assess the efficacy and safety of biologics compared to a placebo in the treatment of EoE patients by performing a comprehensive meta-analysis of existing high-quality, double-blind randomized controlled trials (RCTs)
Current state of biologics in treating eosinophilic esophagitis Eosinophilic esophagitis (EoE) is a chronic, allergen-mediated, eosinophil-predominant, type 2 inflammatory disease that progresses to fibrostenosis of the esophagus if left untreated This review focuses on biologics therapy in EoE
Biologics in the Treatment of Eosinophilic Esophagitis: Ready . . . Eosinophilic esophagitis (EoE) is a chronic disease mediated by environmental allergens and type 2 immune inflammation, which causes significant symptoms including dysphagia and food impaction 1,2 The incidence and prevalence of EoE are rising and untreated disease can lead to significant esophageal stenosis 2,3 Standard treatments include proton-pump inhibitors (PPIs), swallowed topical
Biologics in eosinophilic esophagitis - PubMed Recent findings: There has been an increasing number of biologics under consideration for EoE and several that have undergone clinical trials mAbs that target specific effectors involved in the disease may offer additional clinical and histologic benefit In addition, they offer a more benign adverse effect profile than traditional therapies
Consumer’s Guide to Biologics for Eosinophilic Esophagitis Some biologics are given intravenously (through a needle into a vein) and some by infusion at a clinic or other setting The biologic approved for EoE is self-administered subcutaneously, into the