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Primary Lateral Sclerosis (PLS)_FactSheet-1page. qxd PRIMARY LATERAL SCLEROSIS (PLS) What is PLS? Like ALS, primary lateral sclerosis (PLS) is a progressive degenerative disease of the motor neurons It is characterized by progressive spasticity (involuntary muscle tension and spasms) and it affects the lower limbs, trunk, upper limbs, and bulbar muscles, usually in that order
代谢组VIP值必须要吗？ - 知乎 VIP值（Variable Importance in Projection）在代谢组学分析中不是绝对必须的，但它是一个重要的辅助工具，用于评估代谢物在区分不同样本组中的重要性。VIP值可以帮助筛选出对组间差异有显著贡献的代谢物，特别是当结合PLS-DA（偏最小二乘判别分析）或OPLS-DA分析时。虽然没有硬性规定必须使用VIP值，但