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Brain Banks - ALZFORUM This database lists brain banks around the world that collect central nervous system tissue from various neurodegenerative diseases and normal aging controls The banks share samples and attendant demographic and clinical information with qualified researchers worldwide Many brain banks operate as part of larger consortia that maintain virtual inventories of their combined holdings and offer
Banner Sun Health Research Institute - ALZFORUM This brain bank, biobank, and biospecimen bank derives its donors from the Arizona Study of Aging and Neurodegenerative Disease (AZSAND), a longitudinal clinicopathological study of elderly volunteers living in Maricopa county and metropolitan Phoenix Studies focus on Alzheimer’s and Parkinson
Brain Banks for Alzheimer’s, Parkinson’s Remain Underused Related disorders include DLB, Parkinson’s disease with dementia, multiple system atrophy, and progressive supranuclear palsy Banner recently joined the Parkinson’s Disease Biomarkers Program, a new portal that will enable researchers to submit requests for biomarker data and associated tissue requests to the Banner brain bank, Sieber said
Epilepsy Society Brain and Tissue Bank (ESBTB) | ALZFORUM The ESBTB is the first of its kind in the UK It is dedicated to the study of epilepsy and Sudden Death in Epilepsy (SUDEP), providing brain and other tissue samples to researchers for ethically approved epilepsy research Such research can help elucidate more about why some people develop epilepsy
LX1001 - ALZFORUM Findings In November 2019, investigators at Weill Medical College of Cornell University began a Phase 1 trial evaluating LX1001 in 15 volunteers who carry two APOE4 alleles and have PET- or CSF-confirmed brain amyloid deposition and a clinical diagnosis of mild cognitive impairment to moderate dementia This open-label, dose-ranging study called for a single intrathecal injection of one of
Alzheimers Association International Conference 2020 . . . - ALZFORUM At this year’s virtual Alzheimer’s Association International Conference, researchers from Novartis and the Banner Alzheimer’s Institute presented highly anticipated follow-up data from the massive Generation 1 and 2 Phase 3 trials These were halted when volunteers on the BACE inhibitor umibecestat began to develop subtle memory problems
NSW Brain Bank Network - ALZFORUM The network's pre-mortem donor program, “Using our Brains," accepts donors 18 and older within a specified geographical area Phenotypes collected include Alzheimer’s disease, family history of Alzheimer’s, cognitively normal, healthy normal, dementia with Lewy bodies, frontotemporal dementia
Sydney Brain Bank | ALZFORUM The brain bank receives brain and spinal cord donations from individuals enrolled during life in one of its nine affiliated brain donor programs Donors must live in New South Wales and be older than 18 years The bank collects tissue from donors with sporadic and familial forms of a number of disorders, including Alzheimer’s, Lewy body dementia, Parkinson’s, frontotemporal dementia
Can Donanemab Prevent AD? Phase 3 TRAILBLAZER-ALZ3 Aims to Find Out After a Phase 2 study hinted that donanemab could curb cognitive decline in people with symptomatic AD, the amyloid-targeted drug will soon be evaluated for its ability to prevent the disease According to a July 15 announcement, trial sponsor Eli Lilly and Co will collaborate with the Banner