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Nivolumab in the treatment of metastatic squamous non-small cell lung . . . Abstract Progress in the treatment of patients with advanced stage squamous cell non-small cell lung cancer (NSCLC) has been limited An improvement in the understanding of tumor immunosurveillance has resulted in the development of the immune checkpoint inhibitors such as nivolumab
Nivolumab Approved for Neoadjuvant and Adjuvant Treatment of Non-small . . . The immunotherapy is now approved to treat certain lung cancers before and after surgery The U S Food and Drug Administration (FDA) has approved neoadjuvant nivolumab (Opdivo) with platinum-containing chemotherapy, followed by adjuvant nivolumab alone, for patients with non-small cell lung cancer (NSCLC) that can be surgically removed, is 4 cm or larger or has spread to the lymph nodes, and
Non-Small Cell Lung Cancer (NSCLC) Treatment | OPDIVO® (nivolumab) OPDIVO® (nivolumab) alone, or with YERVOY® (ipilimumab) can be used as an immunotherapy treatment option for adults with certain types of NSCLC Please see Indication and Important Safety Information
Nivolumab plus ipilimumab versus carboplatin-based doublet as first . . . Background: Combined treatment with anti-PD-1 and anti-CTLA-4 antibodies has shown superiority over chemotherapy in patients with advanced non-small-cell lung cancer (NSCLC), but data for older patients (aged ≥70 years) with an Eastern Cooperative Oncology Group (ECOG) performance status of 0-1 or those with an ECOG performance status of 2
Nivolumab and Chemotherapy for Early-Stage Lung Cancer In the CheckMate 816 trial, people with early-stage non-small cell lung cancer (stage IB to IIIA) received either nivolumab (Opdivo) and chemotherapy or chemotherapy alone before surgery
Five-year outcomes with first-line nivolumab plus ipilimumab with 2 . . . Immunotherapy-based regimens are now standard first-line treatments for patients with metastatic non-small cell lung cancer (mNSCLC) Nivolumab and ipilimumab are immune checkpoint inhibitors that block programmed death 1 (PD-1) and cytotoxic T lymphocyte associated protein-4 (CTLA-4), respectively, through distinct but complementary mechanisms of action [1,2] First-line nivolumab plus