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Electrodiagnostic Evaluation of Myopathies - The Myositis Association EMG analysis allows the evaluation of multiple sites and the identification of affected muscles that are not weak on neurologic examination The authors usually perform routine NCSs first, expecting sensory NCSs to be normal in myopathies, unless there is a coexistent neuropathy
Chronic Inflammatory Demyelinating Polyneuropathies (CIDP) and Mimics . . . • Motor conduction blocks are most common finding on NCS, absence of sensory abnormalities • Can also mimic MND (ie ALS) –Absence of any bulbar involvement + demyelinating features on NCS helpful to distinguish pure motor CIDP from MND • Treatment response rate to immunotherapy 70–90% in most series (comparable to classic CIDP)
Mitochondrial Myopathy or Chronic Inflammatory Demyelinating . . . —Bernsen and coworkers1 recently described a patient in whom they found a defect in mitochondrial complex 1 and carnitine deficiency in skeletal muscle However, the clinical features of their patient suggest CIDP
EMG IN CIDP - Cidpusa. org In contrast, examination of nerve biopsies in all 8 patients revealed substantial loss of myelinated fibers; in addition, frequent histologic findings were naked axons, thinly myelinated fibers, and various degrees of onion bulbs These histology findings were identical to those of the 36 other CIDP patients
Clinical Interpretation of Nerve Conduction Studies and . . . CRITICAL POINTS Nerve conduction studies (NCS) and electromyography (EMG) provide objective, localizing, prognostically important data about clinically suspected lesions NCS and EMG also provide peripheral nerve system context about concurrent mononeuropathies, polyneuropathy, myopathy, and other neuromuscular disorders NCS are generally more
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) – My . . . In typical cases of CIDP, EMG NCS reveals a pattern suggestive of demyelinating neuropathy (significantly delayed distal latencies and slowed conduction velocities, abnormal shape of dispersion of motor unit potentials, and relative sparing of sural responses)