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Non-targeted metabolomics and associations with per- and . . . To summarize the application of non-targeted metabolomics in epidemiological studies that assessed metabolite and metabolic pathway alterations associated with per- and polyfluoroalkyl substances (PFAS) exposure
Integrated non-targeted metabolomics and lipidomics reveal mechanisms . . . Herein, non-targeted metabolomics and lipidomics based on liquid chromatography–high resolution mass spectrometry (LC-HRMS) were comprehensively applied to analyze all detectable metabolites, including hydrophilic and lipophilic metabolites (Beale et al , 2022)
Advancing non-target analysis of emerging environmental contaminants . . . Non-target analysis (NTA), facilitated by high-resolution mass spectrometry (HRMS), has emerged as a powerful tool for detecting both known and unknown contaminants in environmental matrices without the need for prior assumptions
Quantitative non-targeted analysis: Bridging the gap between . . . Non-targeted analysis (NTA) is a powerful tool for identifying emerging chemical contaminants NTA can directly support chemical risk characterization but must provide quantitative estimates Quantitative NTA methods exist but do not fully consider estimation uncertainty
Full article: Exploring the non-targeted metabolomic landscape in . . . Therefore, the non-targeted metabolomics approach we have employed enables a profiling of metabolites, using spectral libraries for identification This approach is expected to deepen the understanding of metabolic adaptations resulting from the interplay between exercise and nutritional intervention, and further support previously reported
Non-targeted and targeted metabolomics approaches to diagnosing lung . . . We characterized metabolic alterations in lung cancer using two analytical platforms: a non-targeted metabolic profiling strategy based on proton nuclear magnetic resonance (1 H-NMR) spectroscopy and a targeted metabolic profiling strategy based on rapid resolution liquid chromatography (RRLC)