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Stevens Johnson Syndrome Toxic Epidermal Necrolysis. SJS TEN Stevens–Johnson syndrome toxic epidermal necrolysis, Lyell syndrome, Erythema multiforme exudativum, Ectodermosis erosiva pluriorificialis Authoritative facts from DermNet New Zealand
SJS-TEN images - DermNet SJS-TEN images Images of Stevens Johnson syndrome toxic epidermal necrolysis Authoritative facts from DermNet New Zealand
Severe cutaneous adverse reaction - DermNet What is a severe cutaneous adverse reaction? A severe cutaneous adverse reaction, or SCAR, refers to several distinct conditions Acute generalised exanthematous pustulosis (AGEP) Drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) Stevens–Johnson syndrome toxic epidermal necrolysis (SJS TEN) Common features can be seen
Erythema multiforme: histological features and mechanisms Histology of erythema multiforme A skin biopsy of erythema multiforme (EM) may show in the epidermis epithelium: Apoptotic individual keratinocytes (cellular self-destruction, earliest histological change) Hydropic degeneration of basal keratinocytes (swollen degenerating cells at the base of the epidermis) Intercellular oedema (spongiosis) Blisters within and under the epidermis epithelium
Target and targetoid lesions - DermNet What are atypical target lesions? Atypical target lesions show just two zones and or an indistinct border In erythema multiforme, these lesions are raised (papular) In Stevens-Johnson syndrome toxic epidermal necrolysis (SJS TEN), they are flat (macular) What are targetoid lesions? Targetoid lesions have concentric zones and look similar to target lesions but are not due to erythema
Drug hypersensitivity syndrome. DRESS - DermNet Drug hypersensitivity syndrome, Drug reaction with eosinophilia and systemic symptoms, DRESS, Drug induced hypersensitivity syndrome, DIHS, DRESS syndrome Authoritative facts from DermNet New Zealand
Erythema multiforme - DermNet Erythema multiforme is an immune-mediated, typically self-limiting, mucocutaneous condition characterised by ‘target’ lesions as seen in the images below Treatment is often not needed as episodes are typically self-limiting with no ongoing complications
Stevens Johnson syndrome toxic epidermal necrolysis: nursing management What is Stevens Johnson syndrome toxic epidermal necrolysis? Stevens Johnson syndrome toxic epidermal necrolysis (SJS TEN) is a very severe and acute skin disease, almost always caused by a drug SJS TEN is characterised by an extensive necrosis and detachment of the epidermis, which involves skin and mucosal surfaces (genitals, eyes, and mouth) The nursing care described on this page is
Dermatological emergencies. Erythema multiforme Created 2008 Learning objectives Diagnose, classify and manage erythema multiforme Introduction Erythema multiforme (EM) is conventionally separated into EM minor and EM major It is now separated from Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (T E N ) Clinical features EM minor EM is more common in men than women and 50% are under 20 years of age It is an eruption of