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Survival of motor neuron - Wikipedia SMN deficiency, primarily due to mutations in SMN1, results in widespread splicing defects, especially in spinal motor neurons, and is one cause of spinal muscular atrophy
SMN2 gene: MedlinePlus Genetics The SMN protein is found throughout the body, with highest levels in the spinal cord This protein is one of a group of proteins called the SMN complex, which is important for the maintenance of specialized nerve cells called motor neurons