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What Is a Smudge Cell? Its Meaning in Blood Test Results While some degree of cellular damage can occur during preparation even with healthy blood, the presence of numerous smudge cells indicates that the original cells were abnormally fragile
Smudge Cells: Why would smudge cells show up on my CBC? The smudge cells are likely a result of the inflammation caused by the flare of diverticulitis Followup bloodwork will help determine if things returned to normal or if further investigation is necessary
Lymphocytosis with Smudge Cells Is Not Equivalent to Chronic . . . Chronic lymphocytic leukemia (CLL) often presents with lymphocytosis and smudge cells (SCs) on routine peripheral blood (PB) tests In some cases, these findings are assumed to be sufficient to diagnose CLL
Why Smudge Cells Should Not Be Overlooked in the Differential of . . . While they are typically viewed as artifacts, their presence can be clinically significant, particularly in conditions such as Chronic Lymphocytic Leukemia (CLL) These fragile lymphocytes are more prone to breakage, resulting in an increased number of smudge cells in CLL patients
What are Smudge Cells, Know its Causes, Differential Diagnosis One of the most common causes behind the formation of the smudge cells is the preparation of the blood films Thus, expertise is desired in this area to prevent the formation of the smudge cells
Are Smudge Cells normal? - Causes, Differential Diagnosis, Significance They result from damage to the cell's membrane or cytoskeleton, which causes the cell to appear deformed or "smudged " They are not regarded as normal and may be brought on by a number of illnesses, including blood problems and certain infections
What are Smudge Cells? Do they indicate CLL? - Mayo Clinic Connect If your mom is dealing with smudge cells, I think you’re already aware that this could be an indication of Chronic Lymphocytic Leukemia (CLL), though there are also some other occurrences where cells can be fragile and ‘smear’ when being tested
Understanding Smudge Cells: What They Mean for Your Health Smudge cells are damaged white blood cells seen on blood smears, often linked to fragile cells in conditions like chronic lymphocytic leukemia (CLL) Their presence alone is not diagnostic but may prompt further evaluation
Can Smudge Cells Be a Normal Finding on a Blood Smear? Smudge cells are a finding that can appear on a blood smear These cellular remnants are essentially damaged white blood cells, and their presence on a laboratory report can sometimes cause concern However, it is important to understand that smudge cells can arise in different contexts