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A Comparison of Multivariate Genome-Wide Association Methods We focused on six methods that are implemented in the software packages PLINK, SNPTEST, MultiPhen, BIMBAM, PCHAT and TATES, and also compared them to standard univariate GWAS, analysis of the first principal component of the traits, and meta-analysis of univariate results
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Cost-benefit tradeoff mediates the transition from rule-based to memory . . . Practice improves task performance and changes task execution from rule-based to memory-based processing by incorporating experiences from practice This computational neuroimaging study reveals how the brain learns to perform a task more efficiently with a cost-benefit analysis that selects the optimal strategy
Taxes to red and processed meat to promote sustainable and healthy . . . Background Consumption of red and processed meat is above sustainable and healthy dietary targets in Mexico Policies to promote greater adherence such as taxing meat are needed to reduce consumption Here, we evaluated how price increases to red and processed meat could shift consumption for meat as well as other key food groups Methods Using data from the Mexican National Household Income
NF-YA transcription factors suppress jasmonic acid-mediated . . . - PLOS Author summary In the arms race between host and viruses, plants have sophisticated defense strategies to cope with pathogenic invasion Our previous research has shown that plant hormones, especially JA signaling, play essential roles in plant antiviral defense Therefore, identification of the regulatory components and network of JA signaling is an important contribution to understanding
Allochthonous marsh subsidies enhances food web productivity in an . . . tates organic matter subsidies This suggests that management actions that improve or restore lateral habitat connectivity as well as terrestrial-aquatic linkages may enhance allochthonous subsidies, promoting increased prey resources and ecosystem benefits in estuaries PLOS ONE
A computationally efficient clustering linear combination approach to . . . TATES detected 9 SNPs because it mainly depends on the smallest P-value of the seven univariate tests In summary, the number of SNPs identified by ceCLC is comparable to the largest number of SNPs identified by other tests, which is consistent with our simulation results