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Death receptor 4 - Wikipedia Death receptor 4 (DR4), also known as TRAIL receptor 1 (TRAILR1) and tumor necrosis factor receptor superfamily member 10A (TNFRSF10A), is a cell surface receptor of the TNF-receptor superfamily that binds TRAIL and mediates apoptosis [5][6]
Definition of DR4 - NCI Dictionary of Cancer Terms A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells An increase in the amount or activity of DR4 on cancer cells may kill more cells
What are DR4 agonists and how do they work? - Patsnap DR4, or Death Receptor 4, is a member of the tumor necrosis factor receptor (TNFR) superfamily that plays a crucial role in mediating apoptosis, the process of programmed cell death This receptor has garnered significant attention for its potential use in oncology and other medical fields
Death Receptor 4 - an overview | ScienceDirect Topics Death receptor 4 (DR4) is defined as a member of the tumor necrosis factor (TNF) receptor superfamily that mediates apoptosis in response to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) binding, contributing to extrinsic apoptosis pathways in cells
Differential Regulation of the TRAIL Death Receptors DR4 and DR5 by the . . . From previous studies the regulation of the DR4 and DR5 cell-death pathways appeared similar; nevertheless in this study we screened a library of small interfering RNA (siRNA) for genes, which when silenced, differentially affect DR4- vs DR5-mediated apoptosis
DR4 - Cancer Terminology An increase in the amount or activity of DR4 on cancer cells may kill more cells Also called death receptor 4, TRAIL receptor 1, TRAIL-R1, and tumor necrosis factor receptor superfamily member 10A
Definition of death receptor 4 - NCI Dictionary of Cancer Terms A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells An increase in the amount or activity of death receptor 4 on cancer cells may kill more cells Also called DR4, TRAIL receptor 1, TRAIL-R1, and tumor necrosis factor receptor superfamily member 10A